"Novel Aspects in Acute Lymphoblastic Leukemia" ed. by Stefan Faderl

This book provides a review of every one of its many facets, the chapters from many investigators from around the world cover a number of relevant topics: aspects of the epidemiology of ALL in Hispanics, ophthalmologic manifestations of ALL, overviews of current therapy and drug-resistance mechanisms, novel biological pathways and targets, new drugs in development, and long-term consequences of CNS prophylaxis and therapy.

Contents
Preface
Part 1 Epidemiology
1 Childhood Acute Leukemias in Hispanic Population: Differences by Age Peak and Immunophenotype
Part 2 NK Cell Leukemia
2 Natural Killer Cell Leukemia: Diagnosis, Pathogenesis and Treatment
Part 3 Clinical Manifestations of Acute Lymphoblastic Leukemia
3 Ophthalmological Manifestations in Acute Lymphoblastic Leukemia
4 Acute Lymphoblastic Leukemia: What Have We Learned About the Effects of This Disease and Its Treatment on the Nervous System?
Part 4 Therapy of Acute Lymphoblastic Leukemia
5 Treatment of Pediatric Acute Lymphoblastic Leukemia and Recent Advances
6 Cellular Therapy of ALL
Part 5 Resistance to Therapy
7 Multidrug Resistance Mechanism of Acute Lymphoblastic Leukemia
Part 6 Pathophysiology and Novel Targets
8 Novel Therapeutic Targets in ALL Therapy
9 Aberrant Proliferative and Apoptotic Pathways in Acute Lymphoblastic Leukemia (ALL): Molecular Therapies to Overcome Chemo-Resistance
10 The Role of PAX5 in ALL
11 p53 as a Therapeutic Target in T-ALL