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    Mathematical and Statistical Methods for Genetic Analysis, Second Edition

    Posted By: AvaxGenius
    Mathematical and Statistical Methods for Genetic Analysis, Second Edition

    Mathematical and Statistical Methods for Genetic Analysis, Second Edition by Kenneth Lange
    English | PDF (True) | 2002 | 376 Pages | ISBN : 0387953892 | 30.9 MB

    During the past decade, geneticists have cloned scores of Mendelian disease genes and constructed a rough draft of the entire human genome. The unprecedented insights into human disease and evolution offered by mapping, cloning, and sequencing will transform medicine and agriculture. This revolution depends vitally on the contributions of applied mathematicians, statisticians, and computer scientists. Mathematical and Statistical Methods for Genetic Analysis is written to equip students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. Mathematical, statistical, and computational principles relevant to this task are developed hand in hand with applications to population genetics, gene mapping, risk prediction, testing of epidemiological hypotheses, molecular evolution, and DNA sequence analysis. Many specialized topics are covered that are currently accessible only in journal articles. This second edition expands the original edition by over 100 pages and includes new material on DNA sequence analysis, diffusion processes, binding domain identification, Bayesian estimation of haplotype frequencies, case-control association studies, the gamete competition model, QTL mapping and factor analysis, the Lander-Green-Kruglyak algorithm of pedigree analysis, and codon and rate variation models in molecular phylogeny. Sprinkled throughout the chapters are many new problems.

    Mathematical and Statistical Methods for Genetic Analysis

    Posted By: AvaxGenius
    Mathematical and Statistical Methods for Genetic Analysis

    Mathematical and Statistical Methods for Genetic Analysis by Kenneth Lange
    English | PDF | 1997 | 277 Pages | ISBN : N /A | 21.1 MB

    During the past decade, geneticists have constructed detailed maps of the human genome and cloned scores of Mendelian disease genes. They now stand on the threshold of sequencing the genome in its entirety. The unprecedented insights into human disease and evolution offered by mapping and sequencing will transform medicine and agriculture. This revolution depends vitally on the contributions of applied mathematicians, statisticians, and computer scientists. Mathematical and Statistical Methods for Genetic Analysis is written to equip graduate students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. Mathematical, statistical, and computational principles relevant to this task are developed hand in hand with applications to gene mapping, risk prediction, and the testing of epidemiological hypotheses. The book includes many topics currently accessible only in journal articles, including pedigree analysis algorithms, Markov chain Monte Carlo methods, reconstruction of evolutionary trees, radiation hybrid mapping, and models of recombination. Exercise sets are included.

    Softwaredesign und Entwurfsmuster: Das umfassende Handbuch

    Posted By: Free butterfly
    Softwaredesign und Entwurfsmuster: Das umfassende Handbuch

    Softwaredesign und Entwurfsmuster: Das umfassende Handbuch
    German | 2025 | ISBN: 3367102598 | 268 pages | MOBI | 27 Mb

    VMware vSphere 7

    Posted By: Free butterfly
    VMware vSphere 7

    VMware vSphere 7 by Bertram Wöhrmann
    German | 2021 | ISBN: 3836275783 | 1348 pages | EPUB | 98 Mb

    VBA mit Excel: Das umfassende Handbuch. Konzepte und Techniken der VBA-Programmierung.

    Posted By: Free butterfly
    VBA mit Excel: Das umfassende Handbuch. Konzepte und Techniken der VBA-Programmierung.

    VBA mit Excel: Das umfassende Handbuch. Konzepte und Techniken der VBA-Programmierung. Das Standardwerk für Einsteiger und fortgeschrittene Anwender by Bernd Held
    German | 2018 | ISBN: 3836238217 | 950 pages | EPUB | 47 Mb

    Up the Youth Club: Illuminating a Hidden History

    Posted By: Free butterfly
    Up the Youth Club: Illuminating a Hidden History

    Up the Youth Club: Illuminating a Hidden History by Emma Warren
    English | 2 December 2025 | ISBN: 057138921X | 448 pages | EPUB | 0.66 Mb

    Computer-Netzwerke

    Posted By: Free butterfly
    Computer-Netzwerke

    Computer-Netzwerke
    German | ISBN: 3367107077 | 528 str. pages | MOBI | 29 Mb

    Supper with Love: Vibrant, Delicious, and Comforting Plant-Forward and Pescatarian Recipes for Every Day

    Posted By: Free butterfly
    Supper with Love: Vibrant, Delicious, and Comforting Plant-Forward and Pescatarian Recipes for Every Day

    Supper with Love: Vibrant, Delicious, and Comforting Plant-Forward and Pescatarian Recipes for Every Day by Michelle Braxton
    English | January 16, 2024 | ISBN: 0063256541 | 240 pages | EPUB | 215 Mb

    Cybersecurity Threats and Attacks in the Gaming Industry

    Posted By: Free butterfly
    Cybersecurity Threats and Attacks in the Gaming Industry

    Cybersecurity Threats and Attacks in the Gaming Industry: Secure Game Players' and Developers' Data and Systems (Apress Pocket Guides) by Massimo Nardone
    English | May 29, 2025 | ISBN: 8868814919 | 124 pages | MOBI | 0.37 Mb

    The Great British Bake Off: Comfort Bakes: The official 2024 Great British Bake Off book

    Posted By: Free butterfly
    The Great British Bake Off: Comfort Bakes: The official 2024 Great British Bake Off book

    The Great British Bake Off: Comfort Bakes: The official 2024 Great British Bake Off book by The The Bake Off Team
    English | September 26, 2024 | ISBN: 1408733943 | 256 pages | EPUB | 20 Mb

    Representation Theory: A First Course

    Posted By: Free butterfly
    Representation Theory: A First Course

    Representation Theory: A First Course (Graduate Texts in Mathematics) by William Fulton, Joe Harris
    English | October 22, 1991 | ISBN: 0387975276 | 566 pages | MOBI | 18 Mb

    Nazis in the New World: German Students in the United States, 1933–1941

    Posted By: Free butterfly
    Nazis in the New World: German Students in the United States, 1933–1941

    Nazis in the New World: German Students in the United States, 1933–1941 by Aaron Gillette
    English | May 27, 2025 | ISBN: 1421450771 | 328 pages | PDF | 10 Mb

    When Voisins Can Be Women and When They Cannot – Masculine Generics in French

    Posted By: Free butterfly
    When Voisins Can Be Women and When They Cannot – Masculine Generics in French

    When Voisins Can Be Women and When They Cannot – Masculine Generics in French by Clara Stumm
    English | July 27, 2025 | ISBN: 3662716623 | 292 pages | Epub PDF (True) | 6.33 Mb

    On Privacy and Technology

    Posted By: Free butterfly
    On Privacy and Technology

    On Privacy and Technology by Daniel J. Solove
    English | March 4, 2025 | ISBN: 0197771688 | 136 pages | MOBI | 0.49 Mb

    Staging Monstrous Bodies: Questioning Normative Orders

    Posted By: Free butterfly
    Staging Monstrous Bodies: Questioning Normative Orders

    Staging Monstrous Bodies: Questioning Normative Orders by Michael Mark Chemers, Ekaterina Trachsel, Gerald Siegmund
    English | September 24, 2025 | ISBN: 1032910674 | 217 pages | MP3 | 29 Mb